Rubidium, sodium and ouabain interactions on the influx of rubidium in rat red blood cells
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منابع مشابه
The Kinetics of Ouabain Inhibition and the Partition of Rubidium Influx in Human Red Blood Cells
IN THE DEVELOPMENT OF OUABAIN INHIBITION OF RUBIDIUM INFLUX IN HUMAN RED BLOOD CELLS A TIME LAG CAN BE DETECTED WHICH IS A FUNCTION OF AT LEAST THREE VARIABLES: the concentrations of external sodium, rubidium, and ouabain. The inhibition is antagonized by rubidium and favored by sodium. Similar considerations could be applied to the binding of ouabain to membrane sites. The total influx of rubi...
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The effects of 0.3-10 nM extracellular protons (pH 9.5-8.0) on ouabain-sensitive rubidium influx were determined in 4,4'-diisocyanostilbene-2, 2'-disulfonate (DIDS)-treated human and rat erythrocytes. This treatment clamps the intracellular H. We found that rubidium binds much better to the protonated pump than the unprotonated pump; 13-fold better in rat and 34-fold better in human erythrocyte...
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The effect of Rb on the growth and the development of sugar beet plants (Beta vulgaris, var. MS NB1 x NB4) depends on the Rb concentration, the K supply, and the relative abundance of Na. Rubidium added either to a low or high K solution with or without added Na increased leaf blade size greatly, possibly through an effect on phytohormones or through a "partitioning effect" on the distribution ...
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Red blood cells exposed to ouabain are capable of net Na outflux against an electrochemical gradient; the net outflux is inhibited by the diuretic, furosemide. In ouabain-treated cells, both the unidirectional Na outflux and the unidirectional Na influx are inhibited by furosemide. Furosemide also inhibits the ouabain-sensitive Na-Na exchange accomplished by the Na-K pump in K-free solutions. F...
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Steady state effluxes of potassium and sodium ions were measured on Pisum sativum var. Alaska root segments excised from seedlings which had grown in a nutrient solution containing the major inorganic ions and either (86)Rb as a tracer for K or (22)Na as a tracer for Na. Fluxes appeared to be from 2 cellular compartments, a small compartment with a high flux rate and a larger compartment with a...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1970
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1970.sp009224